1785-52-0Relevant articles and documents
Synthesis, Rearrangement, and Hauser Annulation of 3-Isocyanophthalides
Mal, Dipakranjan,Ghosh, Ketaki,Chakraborty, Soumen
, p. 2473 - 2484 (2015/08/18)
3-Isocyanoisobenzofuran-1(3H)-ones (phthalides) were prepared in two steps from the corresponding phthalaldehydic acids. The 3-isocyanoisobenzofuran-1(3H)-ones are readily rearranged to the corresponding 3-cyanoisobenzofuran-1(3H)-ones using triflic anhyd
Direct access to 1,4-dihydroxyanthraquinones: The Hauser annulation reexamined with p-quinones
Mal, Dipakranjan,Ray, Sutapa,Sharma, Indrajeet
, p. 4981 - 4984 (2008/02/05)
(Chemical Equation Presented) 3-Phenylsulfanylphthalides (e.g. 8a) readily react with p-benzoquinones in the presence of LiOtBu in THF to furnish 1,4-dihydroxyanthraquinones in good yields and one-pot operations.
Diastereoselective Synthesis of Anthracyclinone Precursors
Flock, Markus,Nieger, Martin,Breitmaier, Eberhard
, p. 451 - 456 (2007/10/02)
Cycloaddition of various dienes such as 1-acetoxy-1,3-butadienes 4a, b or 1-phenylethoxy-1,3-butadienes 4c-g with 1,4-anthraquinones 3 affords tetracyclic precursors of anthracyclinone.Using the chiral substituted 1,3-butadienes 4 cycloadducts with d.e. >98percent are obtained.The high stereoselectivity is explained by ? stacking.Key Words: Anthracyclinones / Diels-Alder reactions, asymmetric / 1,4-Anthraquinone / Isoprenyl ethers / 1-Phenylethanol
METAL TEMPLATE ORTHO-ACYLATION OF PHENOLS; A NEW GENERAL APPROACH TO ANTHRACYCLINONES
Sartori, Giovanni,Casnati, Giuseppe,Bigi, Franca,Robles, Pasquale
, p. 1533 - 1536 (2007/10/02)
Direct and mild synthesis of dihydroxyanthraquinones including 4-demethoxy-7-deoxydaunomycinone 8 from ortho-phthaloyl dichloride and hydroquinone derivatives is described.
PHOTOCHROMISM OF PERI-ARYLOXY-p-QUINONES. SYNTHESIS OF SOME SUBSTITUTED PHENOXYNAPHTACENEQUINONES
Gerasimenko, Yu. E.,Poteleshchenko, N. T.,Romanov, V. V.
, p. 1651 - 1656 (2007/10/02)
11-Phenoxy-5,12-naphtacenequinones containing various substituents NO2, Cl, NH2, NHCOCH3, NHCH3, N(COCH3)CH3, N(CH3)2, NHC6H5, NHTs, OH, OCH3, OCOCH3 at position 6 were synthesized.The ability of these compounds to undergo reversible photoisomerization to the corresponding derivatives of 5,11-naphtacenequinone was established, and it was shown that it depends on the nature of the substituent.A series of 6-substituted 12-phenoxy-5,11-naphtacenequinones were obtained by photochemical means.
Oxidative Coupling of Furans and Naphthoquinones: a Potential Route to Anthracyclinones
Bridson, John N.,Bennett, Sharon M.,Butler, Gary
, p. 413 - 414 (2007/10/02)
2-Furyl-1,4-naphthoquinones have been prepared by treatment of mixtures of furans and naphthoquinones with chloranil and other oxidants, and used to synthesize quinizarin and 6,11-dihydroxynaphthacene-5,12-dione in a reaction sequence which promises great versatility.
